![]() Interestingly, in its capacity as a cellular stress sensor, p53 also plays physiological roles beyond tumor suppression as well as causing certain pathological effects. At the molecular level, p53 acts a transcription factor that activates gene expression programs to induce these different responses. Wild-type p53 is a cellular stress sensor, responding to diverse insults such as DNA damage, hyperproliferative signals, and hypoxia by inducing growth arrest or apoptosis, responses thought to be important to tumor suppression. The observations that the p53 gene is mutated in at least half of all human cancers of a wide variety of types and that p53 null mice develop cancer at 100% frequency together underscore the critical role for p53 in tumor suppression. Vice Provost for Undergraduate Education.Office of Vice President for Business Affairs and Chief Financial Officer.Office of VP for University Human Resources.Stanford Woods Institute for the Environment.Stanford Institute for Economic Policy Research (SIEPR).Institute for Stem Cell Biology and Regenerative Medicine.Institute for Human-Centered Artificial Intelligence (HAI).Institute for Computational and Mathematical Engineering (ICME).Freeman Spogli Institute for International Studies.Stanford Doerr School of Sustainability.Bertram Caruthers (Previously Hawthorne).Also, it controls the Kansas City, Kansas Public Library. The district has a number of additional educational and support facilities. The district currently operates 5 high schools, 7 middle schools, and 29 elementary schools and 4 alternative schools. As of 2021, it has approximately 23,690 students enrolled in the district in grades PreK & K-12. Kansas City USD 500, also known as Kansas City Kansas Public Schools, is a public unified school district headquartered in Kansas City, Kansas, United States.
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